Details of CPPsite entry with Sequence RRRRRRRRRRRR |
Primary information | |
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PEPTIDE SEQUENCE | RRRRRRRRRRRR |
CPPsite ID | 2230, 2572, 1037, |
PEPTIDE NAME | EGFP-R12, R12-EGFP, R12 |
CHIRALITY | L, L, L |
LINEAR/CYCLIC | Linear, Linear, Linear |
SOURCE | Synthetic, Synthetic, Synthetic |
CATEGORY | Cationic, Cationic, Cationic |
SUB CELLULAR LOCALIZATION | Cytoplasm, Cytoplasm, Probably cytoplasm and nucleus |
N-TERMINAL MODIFICATION | Conjugated with EGFP, Conjugation with EGFP, Free |
C-TERMINAL MODIFICATION | Free, Free, Conjugation with fluorescein by C-terminal Gly Cys amide |
CHEMICAL MODIFICATION | NA, NA, NA |
UPTAKE EFFICIENCY | Showed increased uptake efficiency, NA, Low |
PROPOSED UPTAKE MECHANISM | NA, NA, Non-endocytic pathway |
INVITRO/INVIVO | In vitro, In vitro and in vivo, In vitro |
CELL LINE | Mouse macrophage-like cell line J774 A.10, The mouse macrophage J774 A.1 cells, RAW 264.7 |
In VIVO MODEL | NA, Zebrafish, NA |
CARGO | Protein (eGFP), Protein (eGFP), Fluorophore (fluorescein) |
PMID | 24746937, 24746937, 11084031 |
PATENT | Unknown, Unknown, Unknown |
Tertiary Structure (Technique) | 2230 (PEPstrMOD), 2572 (PEPstrMOD), 1037 (PEPstrMOD), |