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Details of CPPsite entry with Sequence RRRRRRRRRRRR
Primary information
PEPTIDE SEQUENCERRRRRRRRRRRR
CPPsite ID 2230, 2572, 1037,
PEPTIDE NAMEEGFP-R12, R12-EGFP, R12
CHIRALITYL, L, L
LINEAR/CYCLICLinear, Linear, Linear
SOURCESynthetic, Synthetic, Synthetic
CATEGORYCationic, Cationic, Cationic
SUB CELLULAR LOCALIZATIONCytoplasm, Cytoplasm, Probably cytoplasm and nucleus
N-TERMINAL MODIFICATIONConjugated with EGFP, Conjugation with EGFP, Free
C-TERMINAL MODIFICATIONFree, Free, Conjugation with fluorescein by C-terminal Gly Cys amide
CHEMICAL MODIFICATIONNA, NA, NA
UPTAKE EFFICIENCYShowed increased uptake efficiency, NA, Low
PROPOSED UPTAKE MECHANISMNA, NA, Non-endocytic pathway
INVITRO/INVIVOIn vitro, In vitro and in vivo, In vitro
CELL LINEMouse macrophage-like cell line J774 A.10, The mouse macrophage J774 A.1 cells, RAW 264.7
In VIVO MODELNA, Zebrafish, NA
CARGOProtein (eGFP), Protein (eGFP), Fluorophore (fluorescein)
PMID24746937, 24746937, 11084031
PATENTUnknown, Unknown, Unknown
Tertiary Structure
(Technique)
2230 (PEPstrMOD), 2572 (PEPstrMOD), 1037 (PEPstrMOD),