Details of CPPsite entry with Sequence RRRRRRRRGC |
Primary information | |
---|---|
PEPTIDE SEQUENCE | RRRRRRRRGC |
CPPsite ID | 2669, 2689, |
PEPTIDE NAME | R8, R8 (Alexa) |
CHIRALITY | L, L |
LINEAR/CYCLIC | Linear, Linear |
SOURCE | Synthetic, Synthetic |
CATEGORY | Cationic, Cationic |
SUB CELLULAR LOCALIZATION | NA, Cytosol |
N-TERMINAL MODIFICATION | NA, NA |
C-TERMINAL MODIFICATION | Amidation, Amidation |
CHEMICAL MODIFICATION | NA, NA |
UPTAKE EFFICIENCY | Accumulation of R8 was significantly higher than the other peptides in tumors, NA |
PROPOSED UPTAKE MECHANISM | NA, NA |
INVITRO/INVIVO | In vivo, In vitro |
CELL LINE | NA, HeLa, T98G glioma cells |
In VIVO MODEL | Tumor-xenografted nude mice, NA |
CARGO | Fluorophore (Alexa660), Fluorophore (Alexa) |
PMID | 22285548, 22486588 |
PATENT | Unknown, Unknown |
Tertiary Structure (Technique) | 2669 (PEPstrMOD), 2689 (PEPstrMOD), |