Details of CPPsite entry with Sequence RQIKIWFQNRRMKWKKC |
Primary information | |
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PEPTIDE SEQUENCE | RQIKIWFQNRRMKWKKC |
CPPsite ID | 2331, 2661, |
PEPTIDE NAME | Pen-C-Cy5, Pen-Cys |
CHIRALITY | L, L |
LINEAR/CYCLIC | Linear, Linear |
SOURCE | Protein derived, Protein derived |
CATEGORY | Cationic and amphipathic, Cationic and amphipathic |
SUB CELLULAR LOCALIZATION | Na, Cytoplasm |
N-TERMINAL MODIFICATION | Free, NA |
C-TERMINAL MODIFICATION | Cysteine addition, NA |
CHEMICAL MODIFICATION | NA, Cysteine modification |
UPTAKE EFFICIENCY | Dose dependent uptake, NA |
PROPOSED UPTAKE MECHANISM | Endocytic pathway, Endocytosis |
INVITRO/INVIVO | In vitro, In vitro |
CELL LINE | Undifferentiated malignant glioma rat (F98) cell line, CHO cells, HEK293T cells |
In VIVO MODEL | NA, NA |
CARGO | Fluorophore (Cy5), Nucleic acid (Plasmid DNA) |
PMID | 24276021, 22281502 |
PATENT | Unknown, Unknown |
Tertiary Structure (Technique) | 2331 (PEPstrMOD), 2661 (PEPstrMOD), |