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Details of CPPsite entry with Sequence RQIKIFFQNRRMKFKK
Primary information
PEPTIDE SEQUENCERQIKIFFQNRRMKFKK
CPPsite ID 1134,
PEPTIDE NAMEPen2W2F
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONUneven distribution of peptide with accumulation in centrosmal area and in
N-TERMINAL MODIFICATIONConjugation with fluorescein
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYHigh and comparable to (pAntp) (43-58)
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEPC-12 and V79 cells
CARGOFluorophore (fluorescein)
PMID12849987
PATENTUnknown
Tertiary Structure
(Technique)
1134 (Experimentally determined structure from PDB),