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Details of CPPsite entry with Sequence RLLRLLLRLWRRLLRLLR
Primary information
PEPTIDE SEQUENCERLLRLLLRLWRRLLRLLR
CPPsite ID 2764, 2951,
PEPTIDE NAMEC6, C6
CHIRALITYL, L
LINEAR/CYCLICLinear, Linear
SOURCESynthetic, Synthetic
CATEGORYAmphipathic, NA
SUB CELLULAR LOCALIZATIONCytoplasm, NA
N-TERMINAL MODIFICATIONAcetylation, Free
C-TERMINAL MODIFICATIONAmidation, Free
CHEMICAL MODIFICATIONNA, NA
UPTAKE EFFICIENCYHigh cellular uptake and Cytoplasmic localization of siRNA delivered by C6, NA
PROPOSED UPTAKE MECHANISMNA, NA
INVITRO/INVIVOIn vitro, In vitro
CELL LINECHO-K1 cells, C166-eGFP cells
In VIVO MODELNA, NA
CARGONucleic acid (siRNA), Nucleic acid (siRNA)
PMID23077976
PATENTUnknown, WO 2011/020188 A1
Tertiary Structure
(Technique)
2764 (PEPstrMOD), 2951 (PEPstrMOD),