Details of CPPsite entry with Sequence RLLRLLLRLWRRLLRLLR |
Primary information | |
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PEPTIDE SEQUENCE | RLLRLLLRLWRRLLRLLR |
CPPsite ID | 2764, 2951, |
PEPTIDE NAME | C6, C6 |
CHIRALITY | L, L |
LINEAR/CYCLIC | Linear, Linear |
SOURCE | Synthetic, Synthetic |
CATEGORY | Amphipathic, NA |
SUB CELLULAR LOCALIZATION | Cytoplasm, NA |
N-TERMINAL MODIFICATION | Acetylation, Free |
C-TERMINAL MODIFICATION | Amidation, Free |
CHEMICAL MODIFICATION | NA, NA |
UPTAKE EFFICIENCY | High cellular uptake and Cytoplasmic localization of siRNA delivered by C6, NA |
PROPOSED UPTAKE MECHANISM | NA, NA |
INVITRO/INVIVO | In vitro, In vitro |
CELL LINE | CHO-K1 cells, C166-eGFP cells |
In VIVO MODEL | NA, NA |
CARGO | Nucleic acid (siRNA), Nucleic acid (siRNA) |
PMID | 23077976 |
PATENT | Unknown, WO 2011/020188 A1 |
Tertiary Structure (Technique) | 2764 (PEPstrMOD), 2951 (PEPstrMOD), |