Details of CPPsite entry with Sequence PKKKRKV-AGYLLGKINLKALAALAKKIL-PQMQQNVFQYPGAGMVPQGEANF |
Primary information | |
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PEPTIDE SEQUENCE | PKKKRKV-AGYLLGKINLKALAALAKKIL-PQMQQNVFQYPGAGMVPQGEANF |
CPPsite ID | 2264, 2266, |
PEPTIDE NAME | TP10-SRC1LXXLL, TP10-SRC1(1222-1245) |
CHIRALITY | L, L |
LINEAR/CYCLIC | Linear, Linear |
SOURCE | Chimeric, Chimeric |
CATEGORY | Cationic, Cationic |
SUB CELLULAR LOCALIZATION | Cytoplasm and Nucleus, Cytoplasm and Nucleus |
N-TERMINAL MODIFICATION | Conjugated with NLS, Conjugated with NLS |
C-TERMINAL MODIFICATION | Free, Free |
CHEMICAL MODIFICATION | NA, NA |
UPTAKE EFFICIENCY | Higher uptake efficiency, Lower uptake efficiency than TP10-SRC1LXXLL |
PROPOSED UPTAKE MECHANISM | NA, NA |
INVITRO/INVIVO | In vitro, In vitro |
CELL LINE | MCF-7 cells, MCF-7 cells |
In VIVO MODEL | NA, NA |
CARGO | Fluorophore (FITC ), Fluorophore (FITC ) |
PMID | 24705462, 24705462 |
PATENT | Unknown, Unknown |
Tertiary Structure (Technique) | 2264 (PEPstrMOD), 2266 (I-TASSER), |