Details of CPPsite entry with Sequence Nbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg |
Primary information | |
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PEPTIDE SEQUENCE | Nbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg |
CPPsite ID | 2747, |
PEPTIDE NAME | Polyguanidine comparators 2 |
CHIRALITY | Modified |
LINEAR/CYCLIC | Linear |
SOURCE | Synthetic |
CATEGORY | Cationic and amphipathic |
SUB CELLULAR LOCALIZATION | Cytoplasm |
N-TERMINAL MODIFICATION | Conjugation with 5(6)-Carboxyfluorescein |
C-TERMINAL MODIFICATION | Amidation |
CHEMICAL MODIFICATION | Peptoids (poly-N-substituted glycines) |
UPTAKE EFFICIENCY | Medium (comapre to Polyguanidine comparator 1) |
PROPOSED UPTAKE MECHANISM | Energy-independent internalization |
INVITRO/INVIVO | In vitro |
CELL LINE | MCF-7 cells |
CARGO | Fluorophore [5(6)-Carboxyfluorescein (CF)] |
PMID | 22828784 |
PATENT | Unknown |
Tertiary Structure (Technique) | Not Predicted), |