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Details of CPPsite entry with Sequence Nbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg
Primary information
PEPTIDE SEQUENCENbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg-Nbtg
CPPsite ID 2747,
PEPTIDE NAMEPolyguanidine comparators 2
CHIRALITYModified
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic and amphipathic
SUB CELLULAR LOCALIZATIONCytoplasm
N-TERMINAL MODIFICATIONConjugation with 5(6)-Carboxyfluorescein
C-TERMINAL MODIFICATIONAmidation
CHEMICAL MODIFICATIONPeptoids (poly-N-substituted glycines)
UPTAKE EFFICIENCYMedium (comapre to Polyguanidine comparator 1)
PROPOSED UPTAKE MECHANISMEnergy-independent internalization
INVITRO/INVIVOIn vitro
CELL LINEMCF-7 cells
CARGOFluorophore [5(6)-Carboxyfluorescein (CF)]
PMID22828784
PATENTUnknown
Tertiary Structure
(Technique)
Not Predicted),