Details of CPPsite entry with Sequence NLys-Nspe-Nspe-NLys-Nspe-Nspe-NLys-Nspe-Nspe |
Primary information | |
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PEPTIDE SEQUENCE | NLys-Nspe-Nspe-NLys-Nspe-Nspe-NLys-Nspe-Nspe |
CPPsite ID | 2748, |
PEPTIDE NAME | NLys(1/3) variants 1 |
CHIRALITY | Modified |
LINEAR/CYCLIC | Linear |
SOURCE | Synthetic |
CATEGORY | Cationic and amphipathic |
N-TERMINAL MODIFICATION | Conjugation with 5(6)-Carboxyfluorescein |
C-TERMINAL MODIFICATION | Amidation |
CHEMICAL MODIFICATION | Peptoids (poly-N-substituted glycines) |
UPTAKE EFFICIENCY | Low (Compare to Polyguanidine comparator 1) |
PROPOSED UPTAKE MECHANISM | Probably Energy-dependent Internalization |
INVITRO/INVIVO | In vitro |
CELL LINE | MCF-7 cells |
CARGO | Fluorophore [5(6)-Carboxyfluorescein (CF)] |
PMID | 22828784 |
PATENT | Unknown |
Tertiary Structure (Technique) | Not Predicted), |