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Details of CPPsite entry with Sequence LIRLWSHLIHIWFQNRRLKWKKK
Primary information
PEPTIDE SEQUENCELIRLWSHLIHIWFQNRRLKWKKK
CPPsite ID 2664, 1533,
PEPTIDE NAMEEB1, EB-1
CHIRALITYL, L
LINEAR/CYCLICLinear, Linear
SOURCESynthetic, Protein derived
CATEGORYNA, Amphipathic
SUB CELLULAR LOCALIZATIONCytoplasm, Cytosol
N-TERMINAL MODIFICATIONNA, NA
C-TERMINAL MODIFICATIONNA, Amidation
CHEMICAL MODIFICATIONNA, NA
UPTAKE EFFICIENCYEB1 transfected more than 50% of the cells already indicating its potency as delivery vector, Unknown
PROPOSED UPTAKE MECHANISMEndocytosis, Endocytic pathway
INVITRO/INVIVOIn vitro, In vitro
CELL LINEHEK293T cells, HepG2 cells
In VIVO MODELNA, NA
CARGONucleic acid (Plasmid DNA), Nucleic acid (siRNA)
PMID22281502, 17463227
PATENTUnknown, Unknown
Tertiary Structure
(Technique)
2664 (PEPstrMOD), 1533 (PEPstrMOD),