Details of CPPsite entry with Sequence LIRLWSHLIHIWFQNRRLKWKKK |
Primary information | |
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PEPTIDE SEQUENCE | LIRLWSHLIHIWFQNRRLKWKKK |
CPPsite ID | 2664, 1533, |
PEPTIDE NAME | EB1, EB-1 |
CHIRALITY | L, L |
LINEAR/CYCLIC | Linear, Linear |
SOURCE | Synthetic, Protein derived |
CATEGORY | NA, Amphipathic |
SUB CELLULAR LOCALIZATION | Cytoplasm, Cytosol |
N-TERMINAL MODIFICATION | NA, NA |
C-TERMINAL MODIFICATION | NA, Amidation |
CHEMICAL MODIFICATION | NA, NA |
UPTAKE EFFICIENCY | EB1 transfected more than 50% of the cells already indicating its potency as delivery vector, Unknown |
PROPOSED UPTAKE MECHANISM | Endocytosis, Endocytic pathway |
INVITRO/INVIVO | In vitro, In vitro |
CELL LINE | HEK293T cells, HepG2 cells |
In VIVO MODEL | NA, NA |
CARGO | Nucleic acid (Plasmid DNA), Nucleic acid (siRNA) |
PMID | 22281502, 17463227 |
PATENT | Unknown, Unknown |
Tertiary Structure (Technique) | 2664 (PEPstrMOD), 1533 (PEPstrMOD), |