Details of CPPsite entry with Sequence LGTYTQDFNKFHTFPQTAIGVGAP |
Primary information | |
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PEPTIDE SEQUENCE | LGTYTQDFNKFHTFPQTAIGVGAP |
CPPsite ID | 2226, 2568, 1457, 1458, |
PEPTIDE NAME | EGFP-hcT(9-32), hcT(9-32)-EGFP, hCT (9–32), hCT (9–32) |
CHIRALITY | L, L, L, L |
LINEAR/CYCLIC | Linear, Linear, Linear, Linear |
SOURCE | Protein derived, Protein derived, Protein derived, Protein derived |
CATEGORY | Amphipathic, Amphipathic, Unknown, Unknown |
SUB CELLULAR LOCALIZATION | Cytoplasm, Cytoplasm, Extracellular distribution, Both punctuated cytoplasmic (vesicles) and extracellular distribution |
N-TERMINAL MODIFICATION | Conjugated with EGFP, Conjugation with EGFP, Conjugation with fluorescein, Conjugation with fluorescein |
C-TERMINAL MODIFICATION | Free, Free, Amidation, Amidation |
CHEMICAL MODIFICATION | NA, NA, NA, NA |
UPTAKE EFFICIENCY | Showed increased uptake efficiency, NA, Unknown, Unknown |
PROPOSED UPTAKE MECHANISM | NA, NA, Unknown, Unknown |
INVITRO/INVIVO | In vitro, In vitro and in vivo, In vitro, In vitro |
CELL LINE | Mouse macrophage-like cell line J774 A.6, The mouse macrophage J774 A.1 cells, Calu-3 cells, TR146 cells |
In VIVO MODEL | NA, Zebrafish, NA, NA |
CARGO | Protein (eGFP), Protein (eGFP), Fluorophore (fluorescein), Fluorophore (fluorescein) |
PMID | 24746937, 24746937, 15290867, 15290867 |
PATENT | Unknown, Unknown, Unknown, Unknown |
Tertiary Structure (Technique) | 2226 (PEPstrMOD), 2568 (PEPstrMOD), 1457 (PEPstrMOD), 1458 (PEPstrMOD), |