Details of CPPsite entry with Sequence KRPTMRFRYTWNPMK |
Primary information | |
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PEPTIDE SEQUENCE | KRPTMRFRYTWNPMK |
CPPsite ID | 2735, |
PEPTIDE NAME | 44 |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Synthetic |
UPTAKE EFFICIENCY | primary myelogenous leukaemic cells (AML) showed uptake of CPP44, but not of TAT or CPP2 at comparable concentrations, showed poor penetration into normal fibroblasts |
INVITRO/INVIVO | In vitro and in vivo |
CELL LINE | Many Human neoplastic cells including HeLa, Lovo, A549, MCF-7,MKN45,HepG2, LNCap, KPK,U2OS, RC-15,RD-ES,H28,K562,U251,NHDF |
In VIVO MODEL | NOD-SCID mice model of xenograft human tumour cells |
CARGO | Fluorophore (FITC) |
PMID | 22805558 |
PATENT | Unknown |
Tertiary Structure (Technique) | 2735 (PEPstrMOD), |