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Details of CPPsite entry with Sequence KRPTMRFRYTWNPMK
Primary information
PEPTIDE SEQUENCEKRPTMRFRYTWNPMK
CPPsite ID 2735,
PEPTIDE NAME44
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
UPTAKE EFFICIENCYprimary myelogenous leukaemic cells (AML) showed uptake of CPP44, but not of TAT or CPP2 at comparable concentrations, showed poor penetration into normal fibroblasts
INVITRO/INVIVOIn vitro and in vivo
CELL LINEMany Human neoplastic cells including HeLa, Lovo, A549, MCF-7,MKN45,HepG2, LNCap, KPK,U2OS, RC-15,RD-ES,H28,K562,U251,NHDF
In VIVO MODELNOD-SCID mice model of xenograft human tumour cells
CARGOFluorophore (FITC)
PMID22805558
PATENTUnknown
Tertiary Structure
(Technique)
2735 (PEPstrMOD),