Welcome to Sequence Card of Peptide
Details of CPPsite entry with Sequence KETWWETWWTEWSQPKKKRKV |
| Primary information | |
|---|---|
| PEPTIDE SEQUENCE | KETWWETWWTEWSQPKKKRKV |
| CPPsite ID | 2227, 2313, 2569, 1417, 1763, |
| PEPTIDE NAME | EGFP-Pep-1, PEP-1, Pep-1-EGFP, Pep-1, PN182 (SEQ ID NO: 62) |
| CHIRALITY | L, L, L, L, L |
| LINEAR/CYCLIC | Linear, Linear, Linear, Linear, Linear |
| SOURCE | Synthetic, Synthetic, Synthetic, Chimeric, Synthetic |
| CATEGORY | Amphipathic, NA, Amphipathic, Amphipathic, Unknown |
| SUB CELLULAR LOCALIZATION | NA, NA, NA, Nucleus, Unknown |
| N-TERMINAL MODIFICATION | Conjugated with EGFP, Free, Conjugation with EGFP, Acetylation, Acetylation |
| C-TERMINAL MODIFICATION | Free, Free, Free, Conjugation with FITC at C-terminal cysteamide, Amidation |
| CHEMICAL MODIFICATION | NA, NA, NA, NA, NA |
| UPTAKE EFFICIENCY | NA, Lower uptake efficiency, NA, Unknown, Unknown |
| PROPOSED UPTAKE MECHANISM | NA, NA, NA, Non-endocytic pathway, Unknown |
| INVITRO/INVIVO | In vitro, In vitro and in vivo, In vitro and in vivo, In vitro, In vitro |
| CELL LINE | Mouse macrophage-like cell line J774 A.7, CT26 mouse colon cancer cells, HeLa and Hep3B cells, The mouse macrophage J774 A.1 cells, HS-68 and NIH-3T3, 9 L/LacZ cells |
| In VIVO MODEL | NA, Male Balb/c mice, Zebrafish, NA, NA |
| CARGO | Protein (eGFP), Peptide (Mitochondrial Target Domain of NOXA), Protein (eGFP), Fluorophore (FITC), Nucleic acid (siRNA) |
| PMID | 24746937, 24416126, 24746937, 11731788 |
| PATENT | Unknown, Unknown, Unknown, Unknown, US 20060035815 |
| Tertiary Structure (Technique) | 2227 (PEPstrMOD), 2313 (PEPstrMOD), 2569 (PEPstrMOD), 1417 (PEPstrMOD), 1763 (PEPstrMOD), |