Welcome to Sequence Card of Peptide


Details of CPPsite entry with Sequence INLKKLAKL(Aib)KKIL
Primary information
PEPTIDE SEQUENCEINLKKLAKL(Aib)KKIL
CPPsite ID 2644, 2834,
PEPTIDE NAMETAM-MitP, Mitoparan (MitP)
CHIRALITYModified, Modified
LINEAR/CYCLICLinear, Linear
SOURCESynthetic, Protein derived
CATEGORYNA, NA
SUB CELLULAR LOCALIZATIONNA, Mitochondria
N-TERMINAL MODIFICATIONConjugation with 6-carboxytetramethyl rhodamine, Free
C-TERMINAL MODIFICATIONNA, Amidation
CHEMICAL MODIFICATIONAib, ?-amino isobutyric acid, Aib, ?-amino isobutyric acid
UPTAKE EFFICIENCYHigh (compare to Penetratin), NA
PROPOSED UPTAKE MECHANISMNA, Direct Translocation
INVITRO/INVIVOIn vitro, In vitro
CELL LINEU373 MG cells, Swiss 3T3 cells and bovine spermatozoa
In VIVO MODELNA, NA
CARGOFluorophore (TAMRA), Fluorophore (TAMRA)
PMID22148546, 23585561
PATENTUnknown, Unknown
Tertiary Structure
(Technique)		Not Predicted), 2834 (PEPstrMOD),