Details of CPPsite entry with Sequence GRKKRRQRARPPQC |
Primary information | |
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PEPTIDE SEQUENCE | GRKKRRQRARPPQC |
CPPsite ID | 1027, |
PEPTIDE NAME | Ala substitution mutant of Tat (48-60) |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Protein derived |
CATEGORY | Cationic |
SUB CELLULAR LOCALIZATION | Nucleus and nucleolus |
N-TERMINAL MODIFICATION | Free |
C-TERMINAL MODIFICATION | Conjugation with fluorescein |
UPTAKE EFFICIENCY | Medium (35 % relative to Tat (48-60)) |
PROPOSED UPTAKE MECHANISM | Probably non-endocytic pathway |
INVITRO/INVIVO | In vitro |
CELL LINE | HeLa |
CARGO | Fluorophore (fluorescein) |
PMID | Unknown |
PATENT | Unknown |
Tertiary Structure (Technique) | 1027 (PEPstrMOD), |