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Details of CPPsite entry with Sequence GRKKRRQARAPPQC
Primary information
PEPTIDE SEQUENCEGRKKRRQARAPPQC
CPPsite ID 1028,
PEPTIDE NAMEAla substitution mutant of Tat (48-60)
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONNucleus and nucleolus
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONConjugation with fluorescein
UPTAKE EFFICIENCYLow (15 % relative to Tat (48-60))
PROPOSED UPTAKE MECHANISMProbably non-endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEHeLa
CARGOFluorophore (fluorescein)
PMIDUnknown
PATENTUnknown
Tertiary Structure
(Technique)
1028 (PEPstrMOD),