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Details of CPPsite entry with Sequence FFFFGRRRRRRRRGC
Primary information
PEPTIDE SEQUENCEFFFFGRRRRRRRRGC
CPPsite ID 2693, 2704, 2707,
PEPTIDE NAMEF4R8 (Alexa), F4R8--p27kip1C, F4R8-PAD
CHIRALITYL, L, L
LINEAR/CYCLICLinear, Linear, Linear
SOURCESynthetic, Synthetic, Synthetic
CATEGORYCationic, Cationic, Cationic
SUB CELLULAR LOCALIZATIONCytosol, Cytosol, Cytosol
N-TERMINAL MODIFICATIONNA, NA, NA
C-TERMINAL MODIFICATIONAmidation, Amidation, Amidation
CHEMICAL MODIFICATIONNA, NA, NA
UPTAKE EFFICIENCYUptake was higher in comparison to PasR8, NA, NA
PROPOSED UPTAKE MECHANISMNA, NA, NA
INVITRO/INVIVOIn vitro, In vitro, In vitro
CELL LINEHeLa, T98G glioma cells, HeLa, T98G glioma cells, HeLa, T98G glioma cells
In VIVO MODELNA, NA, NA
CARGOFluorophore (Alexa), Peptide (cyclin-dependent kinase inhibitor), Peptide [(Proapoptotic domain (PAD)]
PMID22486588, 22486588, 22486588
PATENTUnknown, Unknown, Unknown
Tertiary Structure
(Technique)
2693 (PEPstrMOD), 2704 (PEPstrMOD), 2707 (PEPstrMOD),