Details of CPPsite entry with Sequence FFFFGRRRRRRRRGC |
Primary information | |
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PEPTIDE SEQUENCE | FFFFGRRRRRRRRGC |
CPPsite ID | 2693, 2704, 2707, |
PEPTIDE NAME | F4R8 (Alexa), F4R8--p27kip1C, F4R8-PAD |
CHIRALITY | L, L, L |
LINEAR/CYCLIC | Linear, Linear, Linear |
SOURCE | Synthetic, Synthetic, Synthetic |
CATEGORY | Cationic, Cationic, Cationic |
SUB CELLULAR LOCALIZATION | Cytosol, Cytosol, Cytosol |
N-TERMINAL MODIFICATION | NA, NA, NA |
C-TERMINAL MODIFICATION | Amidation, Amidation, Amidation |
CHEMICAL MODIFICATION | NA, NA, NA |
UPTAKE EFFICIENCY | Uptake was higher in comparison to PasR8, NA, NA |
PROPOSED UPTAKE MECHANISM | NA, NA, NA |
INVITRO/INVIVO | In vitro, In vitro, In vitro |
CELL LINE | HeLa, T98G glioma cells, HeLa, T98G glioma cells, HeLa, T98G glioma cells |
In VIVO MODEL | NA, NA, NA |
CARGO | Fluorophore (Alexa), Peptide (cyclin-dependent kinase inhibitor), Peptide [(Proapoptotic domain (PAD)] |
PMID | 22486588, 22486588, 22486588 |
PATENT | Unknown, Unknown, Unknown |
Tertiary Structure (Technique) | 2693 (PEPstrMOD), 2704 (PEPstrMOD), 2707 (PEPstrMOD), |