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Details of CPPsite entry with Sequence DSLKSYWYLQKFSWR
Primary information
PEPTIDE SEQUENCEDSLKSYWYLQKFSWR
CPPsite ID 2729, 1263,
PEPTIDE NAME2, No.15
CHIRALITYL, L
LINEAR/CYCLICLinear, Linear
SOURCESynthetic, Synthetic
CATEGORYNA, Amphipathic
SUB CELLULAR LOCALIZATIONNA, Unknown
N-TERMINAL MODIFICATIONNA, Conjugation with fluorescein
C-TERMINAL MODIFICATIONNA, Free
CHEMICAL MODIFICATIONNA, NA
UPTAKE EFFICIENCYCPP2 was successfully internalized by primary colon adenocarcinoma cells, showed poor penetration into normal fibroblasts, Greater than Tat in CHO cells, while slightly infe
PROPOSED UPTAKE MECHANISMNA, Unknown
INVITRO/INVIVOIn vitro and in vivo, In vitro
CELL LINEMany Human neoplastic cells including HeLa, Lovo, A549, MCF-7,MKN45,HepG2, LNCap, KPK,U2OS, RC-15,RD-ES,H28,K562,U251,NHDF, HeLa, Jurkat and CHO
In VIVO MODELNOD-SCID mice model of xenograft human tumour cells, NA
CARGOFluorophore (FITC), Fluorophore (fluorescein)
PMID22805558, 19956900
PATENTUnknown, Unknown
Tertiary Structure
(Technique)		2729 (PEPstrMOD), 1263 (PEPstrMOD),