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Details of CPPsite entry with Sequence CYGRKKRRQRRR
Primary information
PEPTIDE SEQUENCECYGRKKRRQRRR
CPPsite ID 2513,
PEPTIDE NAMEPTX-N-TAT-LP
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm
N-TERMINAL MODIFICATIONConjugated with PTX via cysteine
C-TERMINAL MODIFICATIONConjugation with liposome-GSH
UPTAKE EFFICIENCYModerate uptake efficiency
PROPOSED UPTAKE MECHANISMEndocytosis
INVITRO/INVIVOIn vitro and in vivo
CELL LINEMurine B16F1 melanoma tumor cells
In VIVO MODELB16F1 tumor-bearing C57 mice
CARGONanoparticle (PTX with liposome), GSH
PMID25449709
PATENTUnknown
Tertiary Structure
(Technique)		2513 (PEPstrMOD),