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Details of CPPsite entry with Sequence CRQIKIWFQNRRMKWKK
Primary information
PEPTIDE SEQUENCECRQIKIWFQNRRMKWKK
CPPsite ID 2233, 2560, 1551,
PEPTIDE NAMEPenetratin, KLA-Pen, P16
CHIRALITYL, L, L
LINEAR/CYCLICLinear, Linear, Linear
SOURCEProtein derived, Chimeric, Protein derived
CATEGORYCationic and amphipathic, Cationic, Unknown
SUB CELLULAR LOCALIZATIONMitochondria, Mitochondria, Unknown
N-TERMINAL MODIFICATIONAcetylation, Conjugated with KLA, NA
C-TERMINAL MODIFICATIONAmidation, Amidation, NA
CHEMICAL MODIFICATIONNA, NA, NA
UPTAKE EFFICIENCYNA, NA, Unknown
PROPOSED UPTAKE MECHANISMNA, NA, Unknown
INVITRO/INVIVOIn vitro, In vitro, In vitro
CELL LINEA549, the neuroblastoma cell line (SK-N-SH), SW480, U251, HEK-293 t, HaCaT, U87, A549, SK-N-SH,SW480, and U251, PC-3
In VIVO MODELNA, NA, NA
CARGOPeptide (KLA) and Nanoparticle (DSPC and DSPG liposomes), Peptide (KLA), Nanoparticle (liposome), Nucleic acid (siRNA)
PMID24796502, 24796502
PATENTUnknown, Unknown, US 20090186802
Tertiary Structure
(Technique)
2233 (PEPstrMOD), 2560 (PEPstrMOD), 1551 (PEPstrMOD),