Details of CPPsite entry with Sequence CRQIKIWFQNRRMKWKK |
Primary information | |
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PEPTIDE SEQUENCE | CRQIKIWFQNRRMKWKK |
CPPsite ID | 2233, 2560, 1551, |
PEPTIDE NAME | Penetratin, KLA-Pen, P16 |
CHIRALITY | L, L, L |
LINEAR/CYCLIC | Linear, Linear, Linear |
SOURCE | Protein derived, Chimeric, Protein derived |
CATEGORY | Cationic and amphipathic, Cationic, Unknown |
SUB CELLULAR LOCALIZATION | Mitochondria, Mitochondria, Unknown |
N-TERMINAL MODIFICATION | Acetylation, Conjugated with KLA, NA |
C-TERMINAL MODIFICATION | Amidation, Amidation, NA |
CHEMICAL MODIFICATION | NA, NA, NA |
UPTAKE EFFICIENCY | NA, NA, Unknown |
PROPOSED UPTAKE MECHANISM | NA, NA, Unknown |
INVITRO/INVIVO | In vitro, In vitro, In vitro |
CELL LINE | A549, the neuroblastoma cell line (SK-N-SH), SW480, U251, HEK-293 t, HaCaT, U87, A549, SK-N-SH,SW480, and U251, PC-3 |
In VIVO MODEL | NA, NA, NA |
CARGO | Peptide (KLA) and Nanoparticle (DSPC and DSPG liposomes), Peptide (KLA), Nanoparticle (liposome), Nucleic acid (siRNA) |
PMID | 24796502, 24796502 |
PATENT | Unknown, Unknown, US 20090186802 |
Tertiary Structure (Technique) | 2233 (PEPstrMOD), 2560 (PEPstrMOD), 1551 (PEPstrMOD), |