Details of CPPsite entry with Sequence CGGGYGRKKRRQRRR |
Primary information | |
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PEPTIDE SEQUENCE | CGGGYGRKKRRQRRR |
CPPsite ID | 2718, |
PEPTIDE NAME | AgNP-TAT |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Protein derived |
CATEGORY | Cationic |
UPTAKE EFFICIENCY | AgNP-TAT showed significant enhancement in killing tumor cells, e.g. up to 24 fold higher compared to its counterpart without TAT-modification |
PROPOSED UPTAKE MECHANISM | phagocytosis or a passive, nonspecific diffusion pathway through the cell membrane |
INVITRO/INVIVO | In vitro and in vivo |
CELL LINE | Caco-2 cells |
In VIVO MODEL | Female nude mice having B16 melanoma |
CARGO | Nanosilver Nanoparticles |
PMID | 22682937 |
PATENT | Unknown |
Tertiary Structure (Technique) | 2718 (PEPstrMOD), |