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Details of CPPsite entry with Sequence CGGGYGRKKRRQRRR
Primary information
PEPTIDE SEQUENCECGGGYGRKKRRQRRR
CPPsite ID 2718,
PEPTIDE NAMEAgNP-TAT
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
UPTAKE EFFICIENCYAgNP-TAT showed significant enhancement in killing tumor cells, e.g. up to 24 fold higher compared to its counterpart without TAT-modification
PROPOSED UPTAKE MECHANISMphagocytosis or a passive, nonspecific diffusion pathway through the cell membrane
INVITRO/INVIVOIn vitro and in vivo
CELL LINECaco-2 cells
In VIVO MODELFemale nude mice having B16 melanoma
CARGONanosilver Nanoparticles
PMID22682937
PATENTUnknown
Tertiary Structure
(Technique)
2718 (PEPstrMOD),