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Details of CPPsite entry with Sequence B-GLRK(NIA)RLRKFRNKIKEK
Primary information
PEPTIDE SEQUENCEB-GLRK(NIA)RLRKFRNKIKEK
CPPsite ID 2602, 2604,
PEPTIDE NAMECF-sC18(NIA), DOTA-sC18(NIA)
CHIRALITYModified, Modified
LINEAR/CYCLICLinear, Linear
SOURCESynthetic, Synthetic
CATEGORYNA, NA
SUB CELLULAR LOCALIZATIONCytoplasmic Vesicles, NA
N-TERMINAL MODIFICATIONAmidation, Amidation
C-TERMINAL MODIFICATIONNA, NA
CHEMICAL MODIFICATIONB, Beta-Alanine; NIA, 2-(2-nitroimidazol-1-yl)acetic acid, B, Beta-Alanine; NIA, 2-(2-nitroimidazol-1-yl)acetic acid ; N terminal chelator DOTA(1,4,7,10-tetraaza-cyclododecane-1,4,7,10-tetraacetic acid)
UPTAKE EFFICIENCYNA, NA
PROPOSED UPTAKE MECHANISMEndocytic pathway, NA
INVITRO/INVIVOIn vitro, In vivo
CELL LINEMCF-7 cells, NA
In VIVO MODELNA, Wistar rats, four female NMRI (nu/nu) mice
CARGOFluorophore (Carboxyfluorescein), Radioactive copper
PMID21956822, 21956822
PATENTUnknown, Unknown
Tertiary Structure
(Technique)		Not Predicted), Not Predicted),