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Details of CPPsite entry with Sequence AGYLLGK[KK2sa4qn4]INLKALAALAKKIL
Primary information
PEPTIDE SEQUENCEAGYLLGK[KK2sa4qn4]INLKALAALAKKIL
CPPsite ID 3003, 3004,
PEPTIDE NAMEPepfect 5, Pepfect 6
CHIRALITYModified, Modified
LINEAR/CYCLICLinear, Linear
SOURCESynthetic, Synthetic
CATEGORYAmphipathic, Amphipathic
SUB CELLULAR LOCALIZATIONNA, NA
N-TERMINAL MODIFICATIONStearylation, Stearylation
C-TERMINAL MODIFICATIONAmidation, Amidation
CHEMICAL MODIFICATIONsa: succinicc acid, qn: novel 2-4 ring systems such as quinoline and naphthalene analogues, sa: succinicc acid, qn: novel 2-4 ring systems such as quinoline and naphthalene analogues
UPTAKE EFFICIENCYNA, NA
PROPOSED UPTAKE MECHANISMEndocytosis, Endocytosis
INVITRO/INVIVOIn vitro, In vitro
CELL LINEHela, Luciferase stable BHK21 cells, Hela, Luciferase stable BHK21 cells, luciferase stable osteosarcoma cells (U2OS)
In VIVO MODELNA, NA
CARGONucleic acid (anti-miR21 ON, siRNA), Nucleic acid (siRNA)
PMIDUnknown
PATENTUS 2014/0140929 A1, US 2014/0140929 A1
Tertiary Structure
(Technique)
Not Predicted), Not Predicted),