Details of CPPsite entry with Sequence AGYLLGKTNLKALAALAKKIL |
Primary information | |
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PEPTIDE SEQUENCE | AGYLLGKTNLKALAALAKKIL |
CPPsite ID | 2439, 2994, |
PEPTIDE NAME | NF1, NF 11 |
CHIRALITY | L, Modified |
LINEAR/CYCLIC | Linear, Linear |
SOURCE | Synthetic, Protein derived |
CATEGORY | Amphipathic, Amphipathic |
SUB CELLULAR LOCALIZATION | Nucleus, NA |
N-TERMINAL MODIFICATION | Stearylation, Stearylation |
C-TERMINAL MODIFICATION | Conjugation with FAM to ?-NH2 group of additional lysine, Amidation |
CHEMICAL MODIFICATION | NA, NA |
UPTAKE EFFICIENCY | Lower uptake efficiency, NA |
PROPOSED UPTAKE MECHANISM | NA, Endocytosis |
INVITRO/INVIVO | In vitro, In vitro |
CELL LINE | HeLa, Hela pLuc 705 cells |
In VIVO MODEL | NA, NA |
CARGO | Nucleic acid (pGL3, siRNA, SCO), Nucleic acid (SCO) |
PMID | 25135660 |
PATENT | Unknown, EP 2 491 952 A1 |
Tertiary Structure (Technique) | 2439 (PEPstrMOD), 2994 (PEPstrMOD), |