Details of CPPsite entry with Sequence AGYLLGKLLOOLAAAALOOLL |
Primary information | |
---|---|
PEPTIDE SEQUENCE | AGYLLGKLLOOLAAAALOOLL |
CPPsite ID | 2720, 2850, 2851, |
PEPTIDE NAME | PF14, PF15, PF14 |
CHIRALITY | Modified, Modified, Modified |
LINEAR/CYCLIC | Linear, Linear, Linear |
SOURCE | Synthetic, Synthetic, Synthetic |
CATEGORY | Cationic, Amphipathic, Amphipathic |
SUB CELLULAR LOCALIZATION | NA, Cytoplasm, Cytoplasm |
N-TERMINAL MODIFICATION | Stearylation, Stearylation, Stearylation |
C-TERMINAL MODIFICATION | Amidation, Amidation, Amidation |
CHEMICAL MODIFICATION | NA, Trifluoromethylquinoline moietie is added at amino froup of Lys7, NA |
UPTAKE EFFICIENCY | NA, NA, NA |
PROPOSED UPTAKE MECHANISM | NA, Endocytic pathway, Endocytic pathway |
INVITRO/INVIVO | In vitro, In vitro, In vitro |
CELL LINE | BHK-21, HepG2, HEK 293 cells, HeLa-, and HeLa pLuc 705-cells, HeLa pLuc705 cells |
In VIVO MODEL | NA, NA, NA |
CARGO | Nucleic acid (siRNA ), Nucleic acid (Cy5-labeled SCO), Nucleic acid (Cy5-labeled SCO) |
PMID | 22698942, 23200958, 21345932 |
PATENT | Unknown, Unknown, Unknown |
Tertiary Structure (Technique) | Not Predicted), Not Predicted), Not Predicted), |