Details of CPPsite entry with Sequence AGYLLGK[KK2sa4qn4]INLKALAALAKKIL |
Primary information | |
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PEPTIDE SEQUENCE | AGYLLGK[KK2sa4qn4]INLKALAALAKKIL |
CPPsite ID | 3003, 3004, |
PEPTIDE NAME | Pepfect 5, Pepfect 6 |
CHIRALITY | Modified, Modified |
LINEAR/CYCLIC | Linear, Linear |
SOURCE | Synthetic, Synthetic |
CATEGORY | Amphipathic, Amphipathic |
SUB CELLULAR LOCALIZATION | NA, NA |
N-TERMINAL MODIFICATION | Stearylation, Stearylation |
C-TERMINAL MODIFICATION | Amidation, Amidation |
CHEMICAL MODIFICATION | sa: succinicc acid, qn: novel 2-4 ring systems such as quinoline and naphthalene analogues, sa: succinicc acid, qn: novel 2-4 ring systems such as quinoline and naphthalene analogues |
UPTAKE EFFICIENCY | NA, NA |
PROPOSED UPTAKE MECHANISM | Endocytosis, Endocytosis |
INVITRO/INVIVO | In vitro, In vitro |
CELL LINE | Hela, Luciferase stable BHK21 cells, Hela, Luciferase stable BHK21 cells, luciferase stable osteosarcoma cells (U2OS) |
In VIVO MODEL | NA, NA |
CARGO | Nucleic acid (anti-miR21 ON, siRNA), Nucleic acid (siRNA) |
PMID | Unknown |
PATENT | US 2014/0140929 A1, US 2014/0140929 A1 |
Tertiary Structure (Technique) | Not Predicted), Not Predicted), |