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This page gives details of CPPsite entry with ID 2852
Primary information
CPPsite ID2852
PEPTIDE SEQUENCEAGYLLGKINLKALAALAKKIL
PEPTIDE NAMEPF6
CHIRALITYModified
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYAmphipathic
SUB CELLULAR LOCALIZATIONCytoplasm
N-TERMINAL MODIFICATIONStearylation
C-TERMINAL MODIFICATIONAmidation
CHEMICAL MODIFICATIONTrifluoromethylquinoline moietie is added at amino froup of Lys7
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro
CELL LINELuc-U2OS and uc-HEK cells
In VIVO MODELC57Bl/6JOlaHsd (Harlan) females
CARGONucleic acid (siRNA)
PMID21245043
PATENTUnknown
LENGTH21
Secondary StructureCHHHHCSSCHHHHHHHTTCCC
SMILESN[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C=O
Tertiary Structure
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  (PEPstrMOD)