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This page gives details of CPPsite entry with ID 2765
Primary information
CPPsite ID2765
PEPTIDE SEQUENCERRRRRRRRRR
PEPTIDE NAMER12-alexa
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYTreating HeLa cells with the CXCR4-specific antagonist FC131 also resulted in a decrease in R12 peptide cellular uptake
PROPOSED UPTAKE MECHANISMMacropinocytosis
INVITRO/INVIVOIn vitro
CELL LINEHeLa cells
CARGOFluorophore (Alexa 568)
PMID23177198
PATENTUnknown
LENGTH10
Secondary StructureCGGGGCCCCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)