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This page gives details of CPPsite entry with ID 2749
Primary information
CPPsite ID2749
PEPTIDE SEQUENCENLys-Nspe-Nspe-NLys-Nspe-Nspe-NLys-Nspe-Nspe-NLys-Nspe-Nspe
PEPTIDE NAMENLys(1/3) variants 2
CHIRALITYModified
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic and amphipathic
SUB CELLULAR LOCALIZATIONPunctated cytoplasmic
N-TERMINAL MODIFICATIONConjugation with 5(6)-Carboxyfluorescein
C-TERMINAL MODIFICATIONAmidation
CHEMICAL MODIFICATIONPeptoids (poly-N-substituted glycines)
UPTAKE EFFICIENCYHigh (Compare to Polyguanidine comparator 1)
PROPOSED UPTAKE MECHANISMEnergy-dependent Internalization
INVITRO/INVIVOIn vitro
CELL LINEMCF-7 cells
CARGOFluorophore [5(6)-Carboxyfluorescein (CF)]
PMID22828784
PATENTUnknown
LENGTH12
Secondary StructureNA
SMILESNA
3-D StructureNot Predicted