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This page gives details of CPPsite entry with ID 2746
Primary information
CPPsite ID2746
PEPTIDE SEQUENCERRRRRRRR
PEPTIDE NAMEPolyguanidine comparators 1
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm
N-TERMINAL MODIFICATIONConjugation with 5(6)-Carboxyfluorescein
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYHigh
PROPOSED UPTAKE MECHANISMEnergy-independent internalization
INVITRO/INVIVOIn vitro
CELL LINEMCF-7 cells
CARGOFluorophore [5(6)-Carboxyfluorescein (CF)]
PMID22828784
PATENTUnknown
LENGTH8
Secondary StructureCCSCSCCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)CO
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)