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This page gives details of CPPsite entry with ID 2663
Primary information
CPPsite ID2663
PEPTIDE SEQUENCERQIRIWFQNRRMRWRRC
PEPTIDE NAMEPenArg-Cys
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
SUB CELLULAR LOCALIZATIONCytoplasm
CHEMICAL MODIFICATIONCysteine modification
UPTAKE EFFICIENCYPenArg-Cys showed transfection efficiencies as high as 40% despite the low charge ratio
PROPOSED UPTAKE MECHANISMEndocytosis
INVITRO/INVIVOIn vitro
CELL LINEHEK293T cells
CARGONucleic acid (Plasmid DNA)
PMID22281502
PATENTUnknown
LENGTH17
Secondary StructureCCCCCCGGGCCSCCCCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CS)C=O
Tertiary Structure
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  (PEPstrMOD)