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This page gives details of CPPsite entry with ID 2554
Primary information
CPPsite ID2554
PEPTIDE SEQUENCERRRRRRRRR
PEPTIDE NAMEFITC-ST2-104
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONVesicles
N-TERMINAL MODIFICATIONConjugation with FITC
C-TERMINAL MODIFICATIONConjugation with CBD3 peptide of CRMP2
UPTAKE EFFICIENCYHigher uptake efficiency
PROPOSED UPTAKE MECHANISMMacropinocytosis, clathrin- mediated endocytosis and caveolae/lipid-raft-mediated endocytosis
INVITRO/INVIVOIn vitro and in vivo
CELL LINEBrain lysates prepared from embryonic day 19 rats
In VIVO MODELFemale Sprague Dawley rats
CARGOPeptide [Ca2+ channel binding domain 9CBD3)] and Fluorophore (FITC)
PMID23106100
PATENTUnknown
LENGTH9
Secondary StructureCGGGGGCCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)