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This page gives details of CPPsite entry with ID 2549
Primary information
CPPsite ID2549
PEPTIDE SEQUENCEMRRIRPRPPRLPRPRPRPLPFPRPGGCYPG
PEPTIDE NAMEBac-ELP-H1
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONConjugation with ELP-Rho
UPTAKE EFFICIENCYSignificantly enhancing brain tumor deposition of the ELP carrier
INVITRO/INVIVOIn vitro and in vivo
CELL LINEHuman U-87-MG and D54 glioma cells along with the rat C6 glioma cells
In VIVO MODELFemale Sprague Dawley rats
CARGOPeptide (Rhodamine labeled ELP)
PMID23372821
PATENTUnknown
LENGTH30
Secondary StructureCTTCCCSSSSSCSCCSSSCCCSSSSSCCCC
SMILESN[C@@H](CCSC)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=
Tertiary Structure
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  (PEPstrMOD)