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This page gives details of CPPsite entry with ID 2543
Primary information
CPPsite ID2543
PEPTIDE SEQUENCEYGRKKRRQRRR
PEPTIDE NAMECF-TAT-substrate
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
SUB CELLULAR LOCALIZATIONCytosol
N-TERMINAL MODIFICATIONConjugation with 5(6)-carboxyfluorescein N-hydroxysuccinimidyl ester
C-TERMINAL MODIFICATIONConjugation with substrate
PROPOSED UPTAKE MECHANISMEndosomal uptake
INVITRO/INVIVOIn vitro
CELL LINEHeLa Cells
CARGOFluorophore (Fluorescein), substrate
PMID23621550
PATENTUnknown
LENGTH11
Secondary StructureCGGGGGGGGCC
SMILESN[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)