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This page gives details of CPPsite entry with ID 2531
Primary information
CPPsite ID2531
PEPTIDE SEQUENCERRGRRG
PEPTIDE NAMEV1
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and Nucleus
N-TERMINAL MODIFICATIONConjugated to FITC modified folding domain via β-alanine–glycine– glycine linker
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYV1 accumulates to a larger extent in cytoplasm than V2, with only a small amount reaching the nucleus
INVITRO/INVIVOIn vitro
CELL LINENIH-3T3 Swiss mice fibroblasts and Jurkat E6 cells
CARGOPeptide (FITC labelled peptide)
PMID25524829
PATENTUnknown
LENGTH6
Secondary StructureCCSSCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC=O
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)