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This page gives details of CPPsite entry with ID 2519
Primary information
CPPsite ID2519
PEPTIDE SEQUENCECHAIYPRH
PEPTIDE NAMET7-LP
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
SUB CELLULAR LOCALIZATIONCytoplasm and Nucleus
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONConjugation with rhodamine LP
UPTAKE EFFICIENCYHigher uptake efficiency
PROPOSED UPTAKE MECHANISMClathrin dependent pathway
INVITRO/INVIVOIn vitro and in vivo
CELL LINEA549
In VIVO MODELBALB/c male athymic nude mice
CARGONanoparticle (Liposome)
PMID25482610
PATENTUnknown
LENGTH8
Secondary StructureCTTTSCCC
SMILESN[C@@H](CS)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1nc[nH]c1)C=O
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)