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This page gives details of CPPsite entry with ID 2515
Primary information
CPPsite ID2515
PEPTIDE SEQUENCEAKKRRQRRRAKKRRQRRR
PEPTIDE NAMEMTat2-Nat
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and Nucleus
N-TERMINAL MODIFICATIONConjugation with FITC
C-TERMINAL MODIFICATIONConjugation with natamycin
UPTAKE EFFICIENCYLower uptake efficiency
PROPOSED UPTAKE MECHANISMEndocytosis
INVITRO/INVIVOIn vitro
CELL LINEHeLa, primary culture of human corneal epithelial cells
CARGOSmall molecule drug (Natamycin), Fluorophore (FITC)
PMID25467959
PATENTUnknown
LENGTH18
Secondary StructureCHHHHHHHHHHHHHSTTC
SMILESN[C@@H](C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
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  (PEPstrMOD)