This page gives details of CPPsite entry with ID 2514 |
Primary information | |
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CPPsite ID | 2514 |
PEPTIDE SEQUENCE | RKKRRQRRRRKKRRQRRR |
PEPTIDE NAME | Tat2-Nat |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Protein derived |
CATEGORY | Cationic |
SUB CELLULAR LOCALIZATION | Cytoplasm and Nucleus |
N-TERMINAL MODIFICATION | Conjugation with FITC |
C-TERMINAL MODIFICATION | Conjugation with natamycin |
UPTAKE EFFICIENCY | Lower uptake efficiency |
PROPOSED UPTAKE MECHANISM | Endocytosis |
INVITRO/INVIVO | In vitro |
CELL LINE | HeLa, primary culture of human corneal epithelial cells |
CARGO | Small molecule drug (Natamycin), Fluorophore (FITC) |
PMID | 25467959 |
PATENT | Unknown |
LENGTH | 18 |
Secondary Structure | CCSCGGGGGHHHHHHHCC |
SMILES | N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |