This page gives details of CPPsite entry with ID 2506 |
Primary information | |
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CPPsite ID | 2506 |
PEPTIDE SEQUENCE | YGRKKRRQRRR |
PEPTIDE NAME | Tat |
CHIRALITY | Modified |
LINEAR/CYCLIC | Linear |
SOURCE | Protein derived |
CATEGORY | Cationic |
SUB CELLULAR LOCALIZATION | Cytoplasm |
N-TERMINAL MODIFICATION | Free |
C-TERMINAL MODIFICATION | Conjugation with Avidin-FITC |
CHEMICAL MODIFICATION | Biotinylation |
UPTAKE EFFICIENCY | KST peptide demonstrated profound penetration into the cells of both lines with the same efficiency as the full-length chap- erone tagged with Alexa489 |
INVITRO/INVIVO | In vitro |
CELL LINE | K-562, A-431, T98G, and 3T3 and 3T3-SV-41 |
CARGO | Protein (Avidin-FITC) |
PMID | 25387797 |
PATENT | Unknown |
LENGTH | 11 |
Secondary Structure | CGGGGGGGGCC |
SMILES | N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |