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This page gives details of CPPsite entry with ID 2500
Primary information
CPPsite ID2500
PEPTIDE SEQUENCEFrFKFrFK
PEPTIDE NAMESingle mitochondrial penetrating peptide
CHIRALITYModified
LINEAR/CYCLICLinear
SOURCESynthetic
SUB CELLULAR LOCALIZATIONMitochondria
N-TERMINAL MODIFICATIONConjugation with Ahx
C-TERMINAL MODIFICATIONAmidation
CHEMICAL MODIFICATIONAhx, 6-aminohexanoic acid
PROPOSED UPTAKE MECHANISMEndocytosis
INVITRO/INVIVOIn vitro
CELL LINEHeLa and CHO cells
CARGODinuclear ruthenium(II) polypyridyl complex
PMID25265566
PATENTUnknown
LENGTH8
Secondary StructureCCCCSSCC
SMILESN[C@@H](Cc1ccccc1)C(=O)N[C@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCC[NH3])C=O
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)