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This page gives details of CPPsite entry with ID 2499
Primary information
CPPsite ID2499
PEPTIDE SEQUENCERRRRRRRR
PEPTIDE NAMER8-lipo
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONConjugation with liposome
UPTAKE EFFICIENCYLow uptake efficiency
PROPOSED UPTAKE MECHANISMEnergy-dependent properties of integrin receptor mediated endocytosis
INVITRO/INVIVOIn vitro and in vivo
CELL LINEMurine glioma cells (C6),bEnd.3 cells and HeLa
In VIVO MODELBalb/c mice
CARGONanoparticle (CFPE-labeled liposomes)
PMID24651033
PATENTUnknown
LENGTH8
Secondary StructureCCSCSCCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)CO
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)