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This page gives details of CPPsite entry with ID 2475 |
| Primary information | |
|---|---|
| CPPsite ID | 2475 |
| PEPTIDE SEQUENCE | GRKKRRQRRR |
| PEPTIDE NAME | Cys(BSH)-TAT |
| CHIRALITY | L |
| LINEAR/CYCLIC | Linear |
| SOURCE | Protein derived |
| CATEGORY | Cationic |
| SUB CELLULAR LOCALIZATION | Cytoplasm |
| N-TERMINAL MODIFICATION | Addition of cysteine and BSH |
| UPTAKE EFFICIENCY | Lower uptake efficiency than 8BSH-11R |
| INVITRO/INVIVO | In vitro and in vivo |
| CELL LINE | U87 DEGFR and PA U87 glioma |
| In VIVO MODEL | Female nude mice (15e20 g, BALB/c Slc-nu/nu) |
| CARGO | BSH |
| PMID | 24452095 |
| PATENT | Unknown |
| LENGTH | 10 |
| Secondary Structure | CCHHHHGGGC |
| SMILES | NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O |
| Tertiary Structure (Technique) | View in Jmol OR Download Structure (PEPstrMOD) |