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This page gives details of CPPsite entry with ID 2473
Primary information
CPPsite ID2473
PEPTIDE SEQUENCERRRRRRRRRRR
PEPTIDE NAMECys(BSH)-Lys[Cys(BSH)-]Arg11-NH2
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm and Nucleus
N-TERMINAL MODIFICATIONAddition of cysteine and BSH
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYLower uptake efficiency than 8BSH-11R
INVITRO/INVIVOIn vitro and in vivo
CELL LINEU87 DEGFR and PA U87 glioma
In VIVO MODELFemale nude mice (15e20 g, BALB/c Slc-nu/nu)
CARGOBSH
PMID24452095
PATENTUnknown
LENGTH11
Secondary StructureCGGGGGGGSCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
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  (PEPstrMOD)