This page gives details of CPPsite entry with ID 2455 |
Primary information | |
---|---|
CPPsite ID | 2455 |
PEPTIDE SEQUENCE | GGVCPKILRRCRRDSDCPGACICRGNGWCGSGSD |
PEPTIDE NAME | MCoTI-M3 |
CHIRALITY | L |
LINEAR/CYCLIC | Cyclic |
SOURCE | Synthetic |
CATEGORY | Cationic |
N-TERMINAL MODIFICATION | Conjugation with Alexa Flour 488 |
C-TERMINAL MODIFICATION | Free |
UPTAKE EFFICIENCY | Low (compared to native MCoTI-II) |
PROPOSED UPTAKE MECHANISM | Macropinocytosis, endocytosis |
INVITRO/INVIVO | In vitro |
CELL LINE | HeLa |
CARGO | Fluorophore (Alexa Fluor 488) |
PMID | 24985034 |
PATENT | Unknown |
LENGTH | 34 |
Secondary Structure | CCCCCSCCCBCSSTTTSCTTCEEETTTEEECSCC |
SMILES | NCC(=O)NCC(=O)N[C@H](C(=O)N[C@@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H]3C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C=O)CC(=O)O)CO)CO)CS[S@@](SC2)C3)Cc2c[nH]c3c2cccc3)CC(=O)N)CCCNC(=N)N)CS)[C@H](CC)C)CSSC1)C)CCC)CC(=O)O)CO)CC(=O)O)CCCNC(=N)N)CCC |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (Homology based) |