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This page gives details of CPPsite entry with ID 2453
Primary information
CPPsite ID2453
PEPTIDE SEQUENCEGGVCPKILKKCRRDSDCPGACICRGNGWCGSGSD
PEPTIDE NAMEMCoTI-M1
CHIRALITYL
LINEAR/CYCLICCyclic
SOURCESynthetic
CATEGORYCationic
N-TERMINAL MODIFICATIONConjugation with Alexa Flour 488
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYEqual to native MCoTI-II
PROPOSED UPTAKE MECHANISMMacropinocytosis, endocytosis
INVITRO/INVIVOIn vitro
CELL LINEHeLa
CARGOFluorophore (Alexa Fluor 488)
PMID24985034
PATENTUnknown
LENGTH34
Secondary StructureCCCCCSCCCBCSSGGGSCTTCEEETTTEEECSCC
SMILESNCC(=O)NCC(=O)N[C@H](C(=O)N[C@@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H]3C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C=O)CC(=O)O)CO)CO)C[S@](SC2)SC3)Cc2c[nH]c3c2cccc3)CC(=O)N)CCCNC(=N)N)CS)[C@H](CC)C)CSSC1)C)CCC)CC(=O)O)CO)CC(=O)O)CCCNC(=N)N)CCCN
Tertiary Structure
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  (Homology based)