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This page gives details of CPPsite entry with ID 2409
Primary information
CPPsite ID2409
PEPTIDE SEQUENCEGLKKLAELFHKLLKLGC
PEPTIDE NAMEEF
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYAmphipathic
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYComparbale to RF but higher than RA
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEHeLa, A549, PC12 and 3T3-L1 cells
PMID24867193
PATENTUnknown
LENGTH17
Secondary StructureCGGGTTTHHHHHHHHTC
SMILESNCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1nc[nH]c1)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CS)C(=O)N
Tertiary Structure
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  (PEPstrMOD)