This page gives details of CPPsite entry with ID 2382 |
Primary information | |
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CPPsite ID | 2382 |
PEPTIDE SEQUENCE | ACSDRFRNCPADEALCGRRRRRRRR |
PEPTIDE NAME | kEA1x8L |
CHIRALITY | L |
LINEAR/CYCLIC | Cyclic |
SOURCE | Synthetic |
CATEGORY | Arginine rich |
SUB CELLULAR LOCALIZATION | Vesicles |
N-TERMINAL MODIFICATION | Extended with Alanine and an 6-aminohexanoic acid (Ahx) spacer |
C-TERMINAL MODIFICATION | Amidation |
CHEMICAL MODIFICATION | All cysteines were capped with iodoacetamide |
PROPOSED UPTAKE MECHANISM | Endocytic pathway |
INVITRO/INVIVO | In vitro |
CELL LINE | HeLa |
CARGO | Fluorophore (FITC) |
PMID | 24697151 |
PATENT | Unknown |
LENGTH | 25 |
Secondary Structure | CBSSSCBSSCTTCHHHHHHTTTTTC |
SMILES | N[C@@H](C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CS)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[ |
Tertiary Structure (Technique) | View in Jmol  OR Download Structure (PEPstrMOD) |