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This page gives details of CPPsite entry with ID 2374
Primary information
CPPsite ID2374
PEPTIDE SEQUENCEARCSDRFRNCPADEALCGR
PEPTIDE NAMEkEA2x1 (Kallikrein inhibitor with external arginines)
CHIRALITYL
LINEAR/CYCLICCyclic
SOURCESynthetic
CATEGORYArginine rich
SUB CELLULAR LOCALIZATIONVesicles
N-TERMINAL MODIFICATIONExtended with Alanine and an 6-aminohexanoic acid (Ahx) spacer
C-TERMINAL MODIFICATIONAmidation
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEHeLa
CARGOFluorophore (FITC)
PMID24697151
PATENTUnknown
LENGTH19
Secondary StructureCCCCTTTSCCSSTTSSTTC
SMILESN[C@@H](C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CS)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
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  (PEPstrMOD)