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This page gives details of CPPsite entry with ID 2344
Primary information
CPPsite ID2344
PEPTIDE SEQUENCEVSRRRRRRGGRRRRK
PEPTIDE NAMEProtamine
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
N-TERMINAL MODIFICATIONConjugation with 5-carboxyfluorescein via a lysine residue
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYLower uptake efficiency
INVITRO/INVIVOIn vitro and in vivo
CELL LINEWong-Kilbourne-derived human conjunctival epithelial cells (NHC)
In VIVO MODELMale SpragueDawley rats and male albino rabbits
CARGOFluorophore [5-carboxyfluorescein (FAM)]
PMID24521351
PATENTUnknown
LENGTH15
Secondary StructureCHHHHHCCCSSTTCC
SMILESN[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCC[NH3])CO
Tertiary Structure
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  (PEPstrMOD)