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This page gives details of CPPsite entry with ID 2342
Primary information
CPPsite ID2342
PEPTIDE SEQUENCERQIKIWFQNRRMKWKKK
PEPTIDE NAMEPenetratin
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic and amphipathic
N-TERMINAL MODIFICATIONConjugation with 5-carboxyfluorescein via a lysine residue
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYHigher uptake efficiency
INVITRO/INVIVOIn vitro and in vivo
CELL LINEWong-Kilbourne-derived human conjunctival epithelial cells (NHC)
In VIVO MODELMale SpragueDawley rats and male albino rabbits
CARGOFluorophore [5-carboxyfluorescein (FAM)]
PMID24521351
PATENTUnknown
LENGTH17
Secondary StructureCCCSCSCTTSSCSCCCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C(=O)N[C@@H](CCCC[NH3])C=O
Tertiary Structure
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  (PEPstrMOD)