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This page gives details of CPPsite entry with ID 2318
Primary information
CPPsite ID2318
PEPTIDE SEQUENCERRLLRRLRR
PEPTIDE NAMER6L3
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic
SUB CELLULAR LOCALIZATIONCytoplasm
N-TERMINAL MODIFICATIONBiotinylation
C-TERMINAL MODIFICATIONAmidation
UPTAKE EFFICIENCYLower than penetratin and R6W5
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro
CELL LINECHO-K1 (WT) and xylose transferase- or GAG-deficient CHO-pgsA745 cells (GAGneg)
CARGOBiotin-gly4
PMID25112713
PATENTUnknown
LENGTH9
Secondary StructureCHHHHHHCC
SMILESN[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=[NH2])N)C(=O)N[C@@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
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  (PEPstrMOD)